ADAPTIL Home Diffuser is a clinically proven solution to help calm and comfort your dog at home. The diffuser works continuously to provide constant comfort, helping your dog or puppy to remain calm and adapt to stressful situations like staying alone, loud noises, thunderstorms and visitors in the home. Plug the diffuser and refill in right side up in an open area where your dog spends the most time. Keep plugged in continuously and replace refills every 30 days. Replace the diffuser device every 6 months. Each diffuser and refill covers up to 750 square feet. Best results are typically seen after 3 to 4 weeks of continuous use. Use only ADAPTIL Refills with ADAPTIL Diffusers